Abnormal expression pattern of cyclin E in tumour cells

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Abnormal expression pattern of cyclin E in tumour cells.

The expression pattern of cyclin E during the cell cycle was studied in normal and tumour cells in culture and in tumour biopsies. This pattern was found to be abnormal in tumour cells. A triple immunostaining protocol, digital microscopy and image analysis were used to find the position of the individual cells in the cell cycle and to measure the nuclear cyclin E levels. In normal cells, the n...

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ژورنال

عنوان ژورنال: International Journal of Cancer

سال: 2003

ISSN: 0020-7136

DOI: 10.1002/ijc.10949